| Arizona Cardinals at St. Louis Rams | ||
| ARI | OUT | OLB Levar Fisher (Knee) OLB Rob Fredrickson (Neck) C Mike Gruttadauria (Knee) WR Frank Sanders (Foot) |
| DOUBTFUL | T John Fina (Ankle) G Pete Kendall (Ankle) | |
| QUESTIONABLE | CB Duane Starks (Ankle) OLB LeVar Woods (Ankle) | |
| PROBABLE | TE Mike Banks (Shoulder) DE Fred Wakefield (Groin) | |
| STL | OUT | T Orlando Pace (Hamstring) QB Kurt Warner (Hand) |
| QUESTIONABLE | OLB Tommy Polley (Ankle) DE Grant Wistrom (Quadricep) | |
| PROBABLE | QB Marc Bulger (Finger) RB Marshall Faulk (Ankle) FB Chris Hetherington (Groin) DT Brian Young (Wrist) | |
| Baltimore Ravens at Houston Texans | ||
| BAL | DOUBTFUL | CB Tommy Knight (Leg) |
| QUESTIONABLE | QB Chris Redman (Back) | |
| PROBABLE | C Mike Flynn (Leg) CB Chris McAlister (Shoulder) S Raymond Perryman (Back) | |
| HOU | DOUBTFUL | WR Jermaine Lewis (Ankle) |
| QUESTIONABLE | T Ryan Young (Knee) | |
| PROBABLE | WR Atnaf Harris (Hip) | |
| Carolina Panthers at Pittsburgh Steelers | ||
| CAR | OUT | MLB Dan Morgan (Shoulder) |
| QUESTIONABLE | OLB Hannibal Navies (Ankle) T Todd Steussie (Knee) | |
| PROBABLE | WR Muhsin Muhammad (Knee) QB Rodney Peete (Groin) TE Wesley Walls (Foot) | |
| PIT | OUT | TE John Allred (Concussion) |
| QUESTIONABLE | ILB James Farrior (Sternum) T Wayne Gandy (Calf) WR Hines Ward (Hamstring) | |
| PROBABLE | ILB Kendrell Bell (Abdomen) RB Jerome Bettis (Knee) SS Lethon Flowers (Quadricep) RB Chris Fuamatu-Ma'afala (Pectoral) | |
| Dallas Cowboys at New York Giants | ||
| DAL | QUESTIONABLE | T Javiar Collins (Knee) CB Derek Ross (Hip) |
| PROBABLE | WR Joey Galloway (Thumb) | |
| NYG | DOUBTFUL | WR Ron Dixon (Knee) |
| QUESTIONABLE | CB Will Allen (Shoulder) OLB Dhani Jones (Ankle) | |
| PROBABLE | MLB Mike Barrow (Concussion) DT Matt Mitrione (Shoulder) OLB Quincy Monk (Ankle) CB William Peterson (Concussion) T Mike Rosenthal (Knee) CB Kato Serwanga (Hamstring) FB Charles Stackhouse (Shoulder) CB Reggie Stephens (Concussion) SS Shaun Williams (Back) | |
| Green Bay Packers at San Francisco 49ers | ||
| GB | PROBABLE | NT Gilbert Brown (Ankle) T Earl Dotson (Back) WR Terry Glenn (Hip) RB Ahman Green (Knee) CB Tod McBride (Thigh) FS Darren Sharper (Hamstring) WR Javon Walker (Ankle) CB Tyrone Williams (Hamstring) |
| SF | OUT | FS Zack Bronson (Foot) OLB Saleem Rasheed (Thigh) CB Jimmy Williams (Injured Reserve) ILB Jamie Winborn (Knee) |
| QUESTIONABLE | FS Ronnie Heard (Ankle) CB Ahmed Plummer (Groin) | |
| PROBABLE | RB Kevan Barlow (Knee) T Derrick Deese (Ankle) RB Garrison Hearst (Knee) G Eric Heitmann (Hand) WR Terrell Owens (Groin) | |
| Indianapolis Colts at Cleveland Browns | ||
| IND | DOUBTFUL | FS Idrees Bashir (Hamstring) FB Detron Smith (Hamstring) |
| QUESTIONABLE | FS Jason Doering (Neck) DE Brad Scioli (Shoulder) MLB Donnel Thompson (Back) | |
| PROBABLE | DT James Cannida (Knee) CB Walt Harris (Ankles) WR Qadry Ismail (Thigh) T Waverly Jackson (Elbow) RB Edgerrin James (Ankle) QB Peyton Manning (Knee) DT David Pugh (Groin) C Jeff Saturday (Ankle) OLB David Thornton (Knee) WR Reggie Wayne (Chest) | |
| CLE | DOUBTFUL | DE Courtney Brown (Knee) WR Dennis Northcutt (Knee) |
| QUESTIONABLE | FS Devin Bush (Hamstring) CB Daylon McCutcheon (Thumb) | |
| Jacksonville Jaguars at Cincinnati Bengals | ||
| JAC | PROBABLE | TE Kyle Brady (Ankles) SS Donovin Darius (Shoulder) DT John Henderson (Knee) RB Elvis Joseph (Hamstring) WR Bobby Shaw (Toe) OLB T.J. Slaughter (Ankle) OLB Eric Westmoreland (Hamstring) |
| CIN | OUT | FS Lamont Thompson (Knee) |
| DOUBTFUL | DE Vaughn Booker (Ribs) | |
| QUESTIONABLE | WR Danny Farmer (Knee) CB Artrell Hawkins (Thigh) WR Peter Warrick (Chest) | |
| PROBABLE | RB Brandon Bennett (Knee) C Rich Braham (Ankle) RB Corey Dillon (Ankle) SS Cory Hall (Shoulder) | |
| Kansas City Chiefs at Denver Broncos | ||
| KC | OUT | G Victor Allotey (Back) |
| QUESTIONABLE | K Morten Andersen (Knee) OLB Quinton Caver (Shoulder) G Donald Willis (Thigh) | |
| PROBABLE | WR Marc Boerigter (Shoulder) DT John Browning (Foot) RB Priest Holmes (Shoulder) CB Eric Warfield (Hamstring) | |
| DEN | PROBABLE | OLB Ian Gold (Knee) QB Brian Griese (Knee) G Steve Herndon (Thigh) OLB John Mobley (Knee) WR Scottie Montgomery (Neck) G Dan Neil (Knee) TE Shannon Sharpe (Elbow) |
| Minnesota Vikings at New Orleans Saints | ||
| MIN | OUT | T Lewis Kelly (Stomach) |
| QUESTIONABLE | MLB Greg Biekert (Calf) FS Ronnie Bradford (Foot) RB Moe Williams (Foot) | |
| PROBABLE | G Corbin Lacina (Illness) T Bryant McKinnie (Illness) | |
| NO | QUESTIONABLE | G LeCharles Bentley (Ankle) QB Aaron Brooks (Shoulder) CB Dale Carter (Shoulder) RB Deuce McAllister (Ankle) OLB Darrin Smith (Ankle) |
| New York Jets at Chicago Bears | ||
| NYJ | QUESTIONABLE | RB LaMont Jordan (Ankle) |
| PROBABLE | TE Chris Baker (Shoulder) CB Aaron Beasley (Head) WR Santana Moss (Ankle) FB Jerald Sowell (Shoulder) P Matt Turk (Back) | |
| CHI | OUT | TE John Davis (Back) QB Jim Miller (Knee) DT Christian Peter (Calf) |
| QUESTIONABLE | CB R.W. McQuarters (Hip) DT Keith Traylor (Leg) G Chris Villarrial (Back) | |
| PROBABLE | SS Damon Moore (Leg) | |
| Oakland Raiders at Miami Dolphins | ||
| OAK | OUT | CB Tory James (Leg) |
| QUESTIONABLE | TE Roland Williams (Toe) CB Charles Woodson (Leg) | |
| MIA | QUESTIONABLE | WR James McKnight (Ankle) |
| PROBABLE | DT Larry Chester (Shoulder) T Mark Dixon (Ankle) OLB Scott Galyon (Shoulder) QB Ray Lucas (Neck) CB Patrick Surtain (Heel) DE Jay Williams (Quadricep) | |
| San Diego Chargers at Buffalo Bills | ||
| SD | QUESTIONABLE | WR Curtis Conway (Shoulder) G Michael Keathley (Ankle) T Damion McIntosh (Ankle) |
| PROBABLE | T Vaughn Parker (Elbow) OLB Carlos Polk (Ankle) | |
| BUF | QUESTIONABLE | T Jonas Jennings (Leg) DE Kendrick Office (Wrist) LB Dominique Stevenson (Head) |
| Seattle Seahawks at Atlanta Falcons | ||
| SEA | OUT | DE Lamar King (Knee) CB Kris Richard (Illness) |
| DOUBTFUL | DE Anton Palepoi (Ankle) T Floyd Womack (Ankle) | |
| QUESTIONABLE | FS Terreal Bierria (Illness) WR Bobby Engram (Toe) QB Matt Hasselbeck (Foot) RB Maurice Morris (Hamstring) CB Shawn Springs (Foot) CB Willie Williams (Foot) | |
| PROBABLE | WR Koren Robinson (Thumb) OLB Anthony Simmons (Ankle) | |
| ATL | QUESTIONABLE | G Kynan Forney (Hamstring) |
| PROBABLE | CB Ray Buchanan (abdomen) RB Warrick Dunn (Ankle) MLB John Holecek (Arm) DE Patrick Kerney (Knee) DE Brady Smith (Back) | |
| Tampa Bay Buccaneers at Detroit Lions | ||
| TB | QUESTIONABLE | SS John Lynch (Neck) DE Ellis Wyms (Ankle) |
| PROBABLE | G Kerry Jenkins (Knee) WR Joe Jurevicius (Ankle) WR Keenan McCardell (Quadricep) CB Dwight Smith (Knee) T Kenyatta Walker (Shoulder) | |
| DET | DOUBTFUL | G Tyrone Hopson (Neck) T Stockar McDougle (Toe) |
| QUESTIONABLE | RB James Stewart (Neck) | |
| PROBABLE | FS LaMar Campbell (Hamstring) WR Larry Foster (Ankle) | |
| Washington Redskins at Philadelphia Eagles | ||
| WAS | QUESTIONABLE | TE Walter Rasby (Foot) QB Danny Wuerffel (Shoulder) |
| PROBABLE | OLB LaVar Arrington (Finger) DT Daryl Gardener (Back) OLB Lemar Marshall (Knee) DE Bruce Smith (Knee) G Brenden Stai (Knee) DE Renaldo Wynn (Groin) | |
| PHI | OUT | DE Derrick Burgess (Foot) QB Donovan McNabb (Ankle) |
| DOUBTFUL | RB Brian Westbrook (Ankle) | |
| QUESTIONABLE | SS Blaine Bishop (Groin) QB Koy Detmer (Elbow) DE Brandon Whiting (Leg) | |
| PROBABLE | DE Hugh Douglas (Knee) DT Paul Grasmanis (Ankle) DE Ndukwe Kalu (Quadricep) RB Dorsey Levens (Leg) G Jermane Mayberry (Knee) WR Todd Pinkston (Hip) CB Bobby Taylor (Concussion) | |
| New England Patriots at Tennessee Titans | ||
| NE | OUT | OLB Matt Chatham (Hand) |
| DOUBTFUL | MLB Tedy Bruschi (Knee) | |
| QUESTIONABLE | G Joe Andruzzi (Knee) WR Deion Branch (Leg) DE Rick Lyle (Back) | |
| TEN | OUT | WR Kevin Dyson (Hamstring) |
| DOUBTFUL | G Zach Piller (Calf) | |
| QUESTIONABLE | WR Eddie Berlin (Concussion) DE Kevin Carter (Ankle) FS Richard Coady (Hamstring) WR Darrell Hill (Ankle) DE Jevon Kearse (Foot) QB Steve McNair (Toe) FS Lance Schulters (Quadricep) | |