| Kansas City Chiefs at Oakland Raiders | ||
| KC | DOUBTFUL | RB Priest Holmes (Hip) SS Greg Wesley (Hamstring) |
| QUESTIONABLE | DE Duane Clemons (Knee) CB Ray Crockett (Shoulder) WR Johnnie Morton (Back) C Casey Wiegmann (Knee) G Donald Willis (Quadricep) | |
| PROBABLE | WR Marc Boerigter (Shoulder/Foot) TE Tony Gonzalez (Shoulder) WR Dante' Hall (Ankle) | |
| OAK | OUT | CB Charles Woodson (Leg) |
| QUESTIONABLE | DE Trace Armstrong (Groin) SS Derrick Gibson (Ankle) CB Tory James (Leg) TE Roland Williams (Toe) | |
| PROBABLE | T Lincoln Kennedy (Groin) | |
| Philadelphia Eagles at New York Giants | ||
| PHI | OUT | DE Derrick Burgess (Foot) QB Donovan McNabb (Ankle) |
| QUESTIONABLE | MLB Keith Adams (Quadricep) SS Blaine Bishop (Groin) WR Todd Pinkston (Toe) | |
| PROBABLE | OLB Shawn Barber (Neck) QB Koy Detmer (Elbow) DT Jeremy Slechta (Concussion) T Tra Thomas (Quadricep) | |
| NYG | QUESTIONABLE | WR Ron Dixon (Knee) CB William Peterson (Knee) |
| PROBABLE | CB Ralph Brown (Concussion) OLB Quincy Monk (Ankle) TE Jeremy Shockey (Illness) FB Charles Stackhouse (Shoulder) G Jason Whittle (Hand) SS Shaun Williams (Back) | |
| Arizona Cardinals at Denver Broncos | ||
| ARI | OUT | WR Frank Sanders (Foot) |
| DOUBTFUL | G Pete Kendall (Ankle) | |
| QUESTIONABLE | CB David Barrett (Groin) CB Duane Starks (Groin) SS Adrian Wilson (Hamstring) | |
| PROBABLE | WR Kevin Kasper (Hip) SS Justin Lucas (Illness) FB Joel Makovicka (Illness) OLB LeVar Woods (Ankle) | |
| DEN | QUESTIONABLE | QB Brian Griese (Knee) |
| PROBABLE | SS Sam Brandon (Knee) MLB Keith Burns (Shoulder) CB Kelly Herndon (Hamstring) WR Ed McCaffrey (Chest) TE Shannon Sharpe (Elbow) | |
| Atlanta Falcons at Cleveland Browns | ||
| ATL | OUT | FB Bob Christian (Concussion) C Roberto Garza (Knee) |
| DOUBTFUL | MLB John Holecek (Arm) | |
| QUESTIONABLE | CB Juran Bolden (Calf) RB T.J. Duckett (Knee) WR Shawn Jefferson (Hamstring) | |
| PROBABLE | CB Ray Buchanan (abdomen) MLB Chris Draft (Back) G Kynan Forney (Back) SS Gerald McBurrows (Neck) OLB Sam Rogers (Groin) MLB Mark Simoneau (Neck) | |
| CLE | QUESTIONABLE | WR Dennis Northcutt (Knee) |
| PROBABLE | FS Devin Bush (Hamstring) | |
| Baltimore Ravens at Pittsburgh Steelers | ||
| BAL | QUESTIONABLE | FB Dameon Hunter (Neck) TE Terry Jones (Thigh) CB Tommy Knight (Thigh) QB Chris Redman (Back) |
| PROBABLE | FB Sam Gash (Leg) WR Randy Hymes (Thigh) DE Adalius Thomas (Thigh) | |
| PIT | OUT | CB Chad Scott (Hand) |
| QUESTIONABLE | RB Jerome Bettis (Knee) ILB James Farrior (Shoulder) | |
| PROBABLE | FS Mike Logan (Back) QB Tommy Maddox (Ankle) WR Lee Mays (Shoulder) | |
| Carolina Panthers at New Orleans Saints | ||
| CAR | QUESTIONABLE | RB Dee Brown (Shoulder) RB Joe Montgomery (Ankle) TE Wesley Walls (Foot) |
| PROBABLE | DT Kris Jenkins (Leg) OLB Kory Minor (Leg) | |
| NO | DOUBTFUL | FS Steve Gleason (Knee) |
| QUESTIONABLE | WR Jerome Pathon (Knee) OLB Darrin Smith (Neck) T Kyle Turley (Back) | |
| Cincinnati Bengals at Buffalo Bills | ||
| CIN | OUT | FS Mark Roman (Knee) |
| QUESTIONABLE | RB Brandon Bennett (Ribs) DE Vaughn Booker (Ribs) DB Lavar Glover (Hamstring) | |
| PROBABLE | OLB Canute Curtis (Ankle) RB Corey Dillon (Thigh) WR Ron Dugans (Achilles) CB Artrell Hawkins (Ankle) DT Bernard Whittington (Groin) | |
| BUF | QUESTIONABLE | LB Dominique Stevenson (Ankle) |
| Dallas Cowboys at Washington Redskins | ||
| DAL | DOUBTFUL | T Solomon Page (Knee) |
| QUESTIONABLE | CB Derek Ross (Hip) | |
| PROBABLE | CB Mario Edwards (Neck) TE James Whalen (Rib) | |
| WAS | OUT | RB Stephen Davis (Shoulder) |
| QUESTIONABLE | QB Danny Wuerffel (Shoulder) | |
| PROBABLE | DT Daryl Gardener (Back) OLB Lemar Marshall (Ankle) DE Carl Powell (Shoulder) DE Bruce Smith (Foot) | |
| Green Bay Packers at New York Jets | ||
| GB | QUESTIONABLE | T Earl Dotson (Back) DE Keith McKenzie (Hamstring) FS Darren Sharper (Knee) |
| PROBABLE | NT Gilbert Brown (Foot) FB Antonio Carter (Shoulder) QB Brett Favre (Knee) CB Tod McBride (Groin) | |
| NYJ | PROBABLE | CB Donnie Abraham (Thigh) |
| Jacksonville Jaguars at Indianapolis Colts | ||
| JAC | QUESTIONABLE | QB Mark Brunell (Hamstring) |
| PROBABLE | T Todd Fordham (Ankle) DE Rob Meier (Groin) WR Bobby Shaw (Toe) WR Jimmy Smith (Shoulder) RB Fred Taylor (Ankle) | |
| IND | OUT | FB Jim Finn (Ankle) |
| DOUBTFUL | WR Qadry Ismail (Head) | |
| QUESTIONABLE | DE Chad Bratzke (Leg) FS Jason Doering (Neck) SS David Gibson (Knee) CB Nicholas Harper (Back) CB Walt Harris (Knee) DE Brad Scioli (Shoulder) FB Detron Smith (Hamstring) OLB Marcus Washington (Knee) RB Ricky Williams (Ankle) | |
| PROBABLE | FS Idrees Bashir (Hip/Hamstring) CB Cliff Crosby (Thigh) T Waverly Jackson (Knee) RB Edgerrin James (Ankle) CB Joseph Jefferson (Thigh/Hand) RB James Mungro (Thigh) | |
| Miami Dolphins at New England Patriots | ||
| MIA | QUESTIONABLE | DE Rob Burnett (Quadricep) DT Larry Chester (Ankle) |
| PROBABLE | T Mark Dixon (Ankle) FB Rob Konrad (Knee) CB Sam Madison (Hip) CB Patrick Surtain (Heel) DE Jason Taylor (Groin) | |
| NE | OUT | TE Daniel Graham (Ribs-Injured Reserve) |
| QUESTIONABLE | G Joe Andruzzi (Knee) WR Deion Branch (Leg) MLB Tedy Bruschi (Knee) TE Cameron Cleeland (Groin) T Kenyatta Jones (Knee) | |
| Minnesota Vikings at Detroit Lions | ||
| MIN | OUT | K Hayden Epstein (Knee) |
| QUESTIONABLE | WR Kelly Campbell (Toe) TE Byron Chamberlain (Ankle) CB Carey Scott (Quadricep) | |
| PROBABLE | CB Tyrone Carter (Ankle) WR Randy Moss (Knee) WR Chris Walsh (Back) CB Brian Williams (Ankle) | |
| DET | OUT | QB Joey Harrington (Heart) TE Mikhael Ricks (Knee) |
| DOUBTFUL | T Stockar McDougle (Toe) | |
| QUESTIONABLE | FS LaMar Campbell (Knee) CB Chris Cash (Shoulder) | |
| Seattle Seahawks at San Diego Chargers | ||
| SEA | OUT | DE Anton Palepoi (Ankle) |
| QUESTIONABLE | FS Terreal Bierria (Knee) WR Bobby Engram (Toe) RB Maurice Morris (Hamstring) G Floyd Wedderburn (Foot) T Floyd Womack (Ankle) | |
| PROBABLE | RB Shaun Alexander (Foot) OLB Anthony Simmons (Ankle) CB Shawn Springs (Foot) TE Jerramy Stevens (Groin) | |
| SD | DOUBTFUL | WR Curtis Conway (Shoulder) |
| QUESTIONABLE | OLB Junior Seau (Ankle) | |
| PROBABLE | T Damion McIntosh (Ankle) T Vaughn Parker (Elbow) | |
| Tampa Bay Buccaneers at Chicago Bears | ||
| TB | QUESTIONABLE | QB Brad Johnson (Back) DT Warren Sapp (Knee) |
| PROBABLE | C Jeff Christy (Knee) MLB Shelton Quarles (Ankle) | |
| CHI | OUT | TE John Davis (Back) OLB Bryan Knight (Knee) DT Christian Peter (Calf) |
| DOUBTFUL | QB Chris Chandler (Head) | |
| QUESTIONABLE | DE Alex Brown (Calf) SS Damon Moore (Leg) DT Keith Traylor (Leg) | |
| PROBABLE | CB R.W. McQuarters (Hip) DE John Stamper (Shoulder) | |
| Tennessee Titans at Houston Texans | ||
| TEN | QUESTIONABLE | T Brad Hopkins (Knee) T Jason Mathews (Back) QB Steve McNair (Ribs) G Zach Piller (Calf) DT John Thornton (Ankle) |
| HOU | OUT | SS Ramon Walker (Knee-injured reserve) |
| QUESTIONABLE | WR Jermaine Lewis (Ankle) | |
| PROBABLE | CB Jason Bell (Shoulder) DE Gary Walker (Thumb) G Fred Weary (Knee) T Ryan Young (Knee) | |
| San Francisco 49ers at St. Louis Rams | ||
| SF | OUT | RB Jamal Robertson (Hamstring) |
| DOUBTFUL | FS Zack Bronson (Foot) OLB Saleem Rasheed (Thigh) ILB Jamie Winborn (Knee) | |
| QUESTIONABLE | WR Terrell Owens (Groin) G Ron Stone (Ankle) | |
| PROBABLE | T Derrick Deese (Ankle) DE Sean Moran (Achilles) DT Josh Shaw (Knee) | |
| STL | OUT | QB Marc Bulger (Spine) DE Grant Wistrom (Knee) |
| DOUBTFUL | OLB Tommy Polley (Ankle) | |
| QUESTIONABLE | T Orlando Pace (Hamstring) | |
| PROBABLE | RB Marshall Faulk (Ankle) CB Travis Fisher (Knee) QB Jamie Martin (Knee) | |