| San Francisco at New York | ||
| SF | OUT | ILB Jeff Ulbrich (Knee) |
| DOUBTFUL | LB Saleem Rasheed (Thigh) | |
| QUESTIONABLE | DE John Engelberger (appendectomy) DT Jim Flanigan (Hamstring) CB Rashad Holman (Ribs) T Matt Willig (Knee) | |
| PROBABLE | FB Fred Beasley (Back) SS Tony Parrish (Back) | |
| NYG | OUT | WR Tim Carter (Back) C Dusty Zeigler (Knee) |
| QUESTIONABLE | RB Tiki Barber (Hamstring) RB Delvin Joyce (Quadricep) DT Lance Legree (Knee) | |
| PROBABLE | MLB Mike Barrow (Knee) QB Kerry Collins (Shoulder) RB Ron Dayne (Neck) WR Daryl Jones (Knee) LB Wesly Mallard (Hip) CB Jason Sehorn (Knee) TE Jeremy Shockey (Ankle) OLB Brandon Short (Hip) RB Damon Washington (Knee) FS Shaun Williams (Knee) | |
| Arizona at Washington | ||
| ARI | OUT | T Anthony Clement (Arm) FS Adrian Wilson (Shoulder) |
| PROBABLE | C Mike Gruttadauria (Neck) | |
| WAS | OUT | OLB Antonio Pierce (Ankle) TE Walter Rasby (Knee) |
| PROBABLE | DT Daryl Gardener (Back) DE Otis Leverette (Knee) OLB Eddie Mason (Shoulder) T Chris Samuels (Ankle) | |
| Atlanta at Green Bay | ||
| ATL | OUT | OLB Chris Draft (Hamstring) LB Will Overstreet (Shoulder) |
| DOUBTFUL | DT Travis Hall (Groin) MLB Mark Simoneau (Groin) OLB Artie Ulmer (Knee) | |
| PROBABLE | OLB Sam Rogers (Groin) T Todd Weiner (Shoulder) | |
| GB | PROBABLE | C Mike Flanagan (Hand) CB Darrien Gordon (Hamstring) CB Tod McBride (Hamstring) |
| Baltimore at Carolina | ||
| BAL | OUT | DB Will Demps (Elbow) |
| DOUBTFUL | CB James Trapp (Chest) | |
| QUESTIONABLE | FS Gary Baxter (Thigh) DT Anthony Weaver (Ankle) | |
| CAR | OUT | RB DeShaun Foster (Knee) DE Kemp Rasmussen (Hamstring) DB Dante Wesley (Hernia) |
| PROBABLE | DT Brentson Buckner (Knee) OLB Mark Fields (Shoulder) DT Sean Gilbert (Knee) K John Kasay (Groin) G Jamar Nesbit (Ankle) DE Mike Rucker (Ankle) | |
| Dallas at Houston | ||
| DAL | OUT | T Tyson Walter (Ankle) |
| DOUBTFUL | WR Reginald Swinton (Hamstring) | |
| QUESTIONABLE | T Flozell Adams (Knee) T Solomon Page (Ankle) | |
| PROBABLE | CB Mario Edwards (Hamstring) FS Lynn Scott (Concussion) OLB Markus Steele (Neck) RB Michael Wiley (Ankle) | |
| Detroit at Miami | ||
| DET | OUT | MLB Clint Kriewaldt (Foot) |
| DOUBTFUL | C Eric Beverly (Calf) | |
| PROBABLE | G Stockar McDougle (Knee) WR Bill Schroeder (Hip) RB James Stewart (Knee) | |
| MIA | OUT | DE David Bowens (Hand) TE Desmond Clark (Forearm) |
| DOUBTFUL | DB Omare Lowe (Ankle) | |
| QUESTIONABLE | CB Patrick Surtain (Groin) | |
| PROBABLE | DT Tim Bowens (Toe) DE Rob Burnett (Hamstring) FS Arturo Freeman (Hamstring) T Todd Wade (Ankle) TE Jed Weaver (Knee) | |
| Indianapolis at Jacksonville | ||
| IND | OUT | FB Jim Finn (Foot) DT Josh Williams (Foot) |
| DOUBTFUL | S Brian Leigeb (Shoulder) | |
| QUESTIONABLE | SS Cory Bird (Hamstring) NT James Cannida (Hamstring) CB Nicholas Harper (Back) CB Walt Harris (Neck) QB Cory Sauter (Foot) | |
| PROBABLE | OLB Greg Favors (Ankle) QB Brock Huard (Hand) DB Joseph Jefferson (Ankle) RB Shyrone Stith (Knee) | |
| JAC | OUT | OLB T.J. Slaughter (Elbow) |
| PROBABLE | CB Ike Charlton (Foot) DE Paul Spicer (Foot) DT Marcus Stroud (Ankle) | |
| Kansas City at Cleveland | ||
| KC | OUT | DT Eric Downing (Hernia) |
| QUESTIONABLE | OLB Larry Atkins (Calf) | |
| PROBABLE | DE Monty Beisel (Ankle) CB Ray Crockett (Neck) MLB Mike Maslowski (Ankle) | |
| CLE | DOUBTFUL | SS Earl Little (Ankle) LB Ben Taylor (Hamstring) |
| QUESTIONABLE | DT Kenard Lang (Ankle) TE Aaron Shea (Shoulder) | |
| PROBABLE | QB Tim Couch (Forearm) | |
| Minnesota at Chicago | ||
| MIN | QUESTIONABLE | WR Nick Davis (Hamstring) WR Cedric James (Hand) FB Harold Morrow (Hamstring) LB Raonall Smith (Shoulder) |
| PROBABLE | G Corbin Lacina (Ankle) | |
| CHI | OUT | WR Ahmad Merritt (Hand) |
| QUESTIONABLE | DT Christian Peter (Thumb) G Chris Villarrial (Thumb) | |
| PROBABLE | DT Alfonso Boone (Ankle) FS Mike Brown (Hand) T Marc Colombo (Foot) | |
| New Orleans at Tampa Bay | ||
| NO | QUESTIONABLE | DE Darren Howard (Groin) WR Jake Reed (Hamstring) G Wally Williams (Knee) |
| PROBABLE | P Toby Gowin (Hip) DB Mel Mitchell (Ankle) DE Derrius Monroe (Knee) | |
| TB | QUESTIONABLE | G Cosey Coleman (Knee) FB Jameel Cook (Ankle) DT Buck Gurley (Ankle) |
| New York at Buffalo | ||
| NYJ | OUT | CB Jamie Henderson (Shoulder) |
| QUESTIONABLE | DT Larry Webster (Knee) | |
| PROBABLE | DE John Abraham (Knee) SS Sam Garnes (Hand) | |
| BUF | QUESTIONABLE | RB Sammy Morris (Ankle) |
| Philadelphia at Tennessee | ||
| PHI | OUT | WR Freddie Milons (Leg) |
| QUESTIONABLE | DB Lito Sheppard (Quadricep) | |
| PROBABLE | OLB Quinton Caver (Knee) DB Michael Lewis (Ankle) OLB Ike Reese (Knee) | |
| TEN | QUESTIONABLE | MLB Frank Chamberlin (Neck) FS Richard Coady (Ankle) DE Henry Ford (Ankle) DE Jevon Kearse (Tricep) DT John Thornton (Ankle) |
| San Diego at Cincinnati | ||
| SD | DOUBTFUL | SS Robert Carswell (Knee) |
| QUESTIONABLE | CB Tay Cody (Foot) RB Terrell Fletcher (Ankle) FB Joey Goodspeed (Ankle) | |
| CIN | PROBABLE | TE Sean Brewer (Knee) G Mike Goff (Leg) G Victor Leyva (Ankle) OLB Takeo Spikes (Chest) WR Michael Westbrook (Wrist) |
| Seattle at Oakland | ||
| SEA | OUT | DT John Hilliard (Knee) |
| DOUBTFUL | DT John Randle (Knee) | |
| QUESTIONABLE | QB Trent Dilfer (Knee) | |
| PROBABLE | OLB Anthony Simmons (Knee) | |
| OAK | OUT | G Mo Collins (Knee) |
| DOUBTFUL | P Shane Lechler (Quadricep) | |
| PROBABLE | FS Anthony Dorsett (Foot) OLB Bill Romanowski (Back) RB Tyrone Wheatley (Knee) | |
| St. Louis at Denver | ||
| STL | OUT | WR Troy Edwards (Knee) FB James Hodgins (Foot) |
| QUESTIONABLE | C Frank Garcia (Ankle) DE Leonard Little (Thigh) | |
| PROBABLE | QB Jamie Martin (Shoulder) G Adam Timmerman (Knee) | |
| DEN | OUT | G Lennie Friedman (Thumb) |
| QUESTIONABLE | WR Kevin Kasper (Rib) | |
| PROBABLE | RB KaRon Coleman (Ankle) DT Lional Dalton (Ankle) K Jason Elam (Hamstring) DT Chester McGlockton (Knee) CB Tyrone Poole (Thigh) DB Lenny Walls (Ankle) | |
| Pittsburgh at New England | ||
| PIT | PROBABLE | ILB Kendrell Bell (Ankle) OLB Clark Haggans (Knee) DT Chris Hoke (Ribs) G Kendall Simmons (Hamstring) WR Hines Ward (Appendectomy) |
| NE | QUESTIONABLE | CB Tommy Knight (Leg) T Steve Neal (Shoulder) |