| Arizona at San Francisco | ||
| ARI | OUT | T Anthony Clement (Arm) CB Duane Starks (Neck) |
| QUESTIONABLE | DE Kyle Vanden Bosch (Ribs) | |
| PROBABLE | CB David Barrett (Back) G Chris Dishman (Knee) OLB Levar Fisher (Knee) | |
| SF | OUT | FS Zack Bronson (Foot) ILB Jamie Winborn (Knee) |
| DOUBTFUL | OLB Saleem Rasheed (Thigh) OLB Frank Strong (Shoulder) | |
| QUESTIONABLE | RB Garrison Hearst (Hamstring) TE Eric Johnson (Back) FB Paul Smith (Hamstring) | |
| PROBABLE | DE John Engelberger (Ankle) WR Terrell Owens (Heel) WR J.J. Stokes (Knee) | |
| Atlanta at New Orleans | ||
| ATL | OUT | WR Darrin Chiaverini (Quadricep) C Roberto Garza (Foot) |
| DOUBTFUL | RB T.J. Duckett (Foot) CB Kevin Mathis (Knee) T Todd Weiner (Calf) | |
| QUESTIONABLE | FB Bob Christian (Concussion) | |
| PROBABLE | CB Juran Bolden (Hip) OLB Matt Stewart (Ribs) OLB John Thierry (neck) | |
| NO | OUT | OLB Travis Carroll (Leg) CB Michael Hawthorne (Knee) |
| DOUBTFUL | OLB J.R. Johnson (Hamstring) RB Fred McAfee (Hamstring) DE Willie Whitehead (Leg) | |
| QUESTIONABLE | MLB Charlie Clemons (Groin) CB Keyuo Craver (Knee) DT Norman Hand (Hamstring) WR Donte' Stallworth (Hamstring) | |
| Chicago at Minnesota | ||
| CHI | OUT | C Patrick Mannelly (Knee) WR David Terrell (Foot) DT Ted Washington (Ankle) |
| QUESTIONABLE | TE Fred Baxter (Side) TE John Davis (Side) CB R.W. McQuarters (Hamstring) | |
| PROBABLE | C Olin Kreutz (Ankle) QB Jim Miller (Elbow) DE Bryan Robinson (Ankle) | |
| MIN | OUT | RB Doug Chapman (Stomach) DT Talance Sawyer (Knee) |
| QUESTIONABLE | WR D'Wayne Bates (Back) | |
| PROBABLE | C Matt Birk (Knee) CB Tyrone Carter (Knee) CB Corey Chavous (Ankle) DT Chris Hovan (Leg) | |
| Cleveland at New York | ||
| CLE | OUT | CB Corey Fuller (Hamstring) SS Robert Griffith (Shoulder) OLB Ben Taylor (Hamstring) |
| QUESTIONABLE | QB Kelly Holcomb (Knee) WR Andre King (Toe) CB Daylon McCutcheon (Elbow) | |
| PROBABLE | FS Devin Bush (Groin) | |
| NYJ | QUESTIONABLE | FS Jon McGraw (Shoulder) |
| Denver at New England | ||
| DEN | PROBABLE | SS Sam Brandon (Knee) MLB Keith Burns (Hand) DT Chester McGlockton (Leg) DT Monsanto Pope (Ankle) TE Shannon Sharpe (Knee) |
| NE | QUESTIONABLE | G Joe Andruzzi (Knee) WR Troy Brown (Knee) TE Daniel Graham (Shoulder) DE Rick Lyle (Back) DE Anthony Pleasant (Shoulder) C Grey Ruegamer (Foot) |
| Detroit at Buffalo | ||
| DET | DOUBTFUL | WR Eddie Drummond (Ankle) OLB Clint Kriewaldt (Foot) |
| QUESTIONABLE | RB Aveion Cason (Ankle) TE John Owens (Shoulder) TE Mikhael Ricks (Groin) WR Bill Schroeder (Ankle) | |
| PROBABLE | DT Shaun Rogers (Thumb) FB Cory Schlesinger (Back) FS Brian Walker (Toe) | |
| BUF | DOUBTFUL | CB Antoine Winfield (Knee) |
| QUESTIONABLE | FS Tony Driver (Hip) TE Dave Moore (Hand) T Mike Williams (Hamstring) | |
| Houston at Jacksonville | ||
| HOU | QUESTIONABLE | CB Jason Bell (Arm) SS Eric Brown (Shoulder) TE Rod Rutledge (Foot) |
| PROBABLE | OLB Erik Flowers (Ankle) CB Jason Simmons (Hamstring) T Ryan Young (Groin) | |
| JAC | QUESTIONABLE | WR Pat Johnson (Abdomen) |
| PROBABLE | RB Stacey Mack (Ankle) WR Bobby Shaw (Toe) DT Larry Smith (Knee) T Zach Wiegert (Knee) | |
| Indianapolis at Washington | ||
| IND | OUT | TE Joe Dean Davenport (Shoulder) |
| DOUBTFUL | DT Josh Williams (Foot) | |
| QUESTIONABLE | SS Cory Bird (Hip) T Adam Meadows (Hip) DT Larry Tripplett (Shoulder) | |
| PROBABLE | DT James Cannida (Thumb) CB Cliff Crosby (Knee) T Tarik Glenn (Calf) WR Qadry Ismail (Knee) TE Marcus Pollard (Knee) WR Troy Walters (Shoulder) | |
| WAS | QUESTIONABLE | T Chris Samuels (Ankle) G Brenden Stai (Knee) QB Danny Wuerffel (Shoulder) |
| PROBABLE | OLB LaVar Arrington (Wrist) DT Daryl Gardener (Back) DE Renaldo Wynn (Knee) | |
| Oakland at Kansas City | ||
| OAK | OUT | CB Phillip Buchanon (Wrist) |
| DOUBTFUL | RB Randy Jordan (Groin) RB Tyrone Wheatley (Hamstring) | |
| QUESTIONABLE | CB Clarence Love (Leg) FB Jon Ritchie (Elbow) T Barry Sims (Toe) CB Charles Woodson (Shoulder) FS Rod Woodson (Quadricep) | |
| PROBABLE | OLB Bill Romanowski (Ankle) | |
| KC | QUESTIONABLE | RB Michael Cloud (Foot) TE Jason Dunn (Shoulder) T Marcus Spears (Elbow) SS Greg Wesley (Shoulder) |
| PROBABLE | K Morten Andersen (Hamstring) CB William Bartee (Back) QB Trent Green (Ankle) FS Shaunard Harts (Shoulder) | |
| Pittsburgh at Baltimore | ||
| PIT | OUT | RB Jerome Bettis (Knee) C Jeff Hartings (Knee) |
| DOUBTFUL | TE Jerame Tuman (Quadricep) | |
| QUESTIONABLE | TE John Allred (Calf) | |
| PROBABLE | DE Rodney Bailey (Ribs) C Mike Schneck (Elbow) T Marvel Smith (Knee) | |
| BAL | DOUBTFUL | DE Michael McCrary (Knee) |
| QUESTIONABLE | K J.R. Jenkins (Leg) ILB Ray Lewis (Shoulder) | |
| PROBABLE | T Ethan Brooks (Back) G Jason Thomas (Calf) | |
| Seattle at Dallas | ||
| SEA | OUT | G Steve Hutchinson (Leg) |
| QUESTIONABLE | TE Ryan Hannam (Flu) OLB Anthony Simmons (Ankle) CB Shawn Springs (Foot) TE Jerramy Stevens (Ankle) | |
| DAL | OUT | G Matt Lehr (Knee) T Marques McFadden (Shoulder) MLB Dat Nguyen (Wrist) |
| DOUBTFUL | CB Pete Hunter (Ankle) | |
| QUESTIONABLE | G Larry Allen (Ankle) FS Lynn Scott (Toe) | |
| PROBABLE | C Andre Gurode (Toe) RB Emmitt Smith (Ankle) | |
| Tampa Bay at Carolina | ||
| TB | DOUBTFUL | QB Brad Johnson (Rib) WR Keenan McCardell (Scapula) |
| PROBABLE | C Jeff Christy (Knee) CB Brian Kelly (Knee) DT Warren Sapp (Knee) CB Dwight Smith (Stomach Virus) RB Aaron Stecker (Stomach Virus) | |
| CAR | OUT | RB DeShaun Foster (Knee) QB Rodney Peete (Knee) |
| QUESTIONABLE | OLB Mark Fields (Groin) SS Mike Minter (Arm) MLB Dan Morgan (Groin) TE Wesley Walls (Finger) QB Chris Weinke (Concussion) OLB Will Witherspoon (Head) | |
| Tennessee at Cincinnati | ||
| TEN | OUT | RB Robert Holcombe (Hip) DE Jevon Kearse (Foot) |
| QUESTIONABLE | FB Greg Comella (Shoulder) CB Mike Echols (Leg) MLB Randall Godfrey (Ankle) DE Carlos Hall (Knee) WR Derrick Mason (Shoulder) | |
| CIN | DOUBTFUL | DE Vaughn Booker (Knee) |
| QUESTIONABLE | TE Sean Brewer (Knee) FS Mark Roman (Head) MLB Adrian Ross (Knee) WR Michael Westbrook (Hamstring) | |
| PROBABLE | G Mike Goff (Knee) FS Lamont Thompson (Knee) | |
| New York at Philadelphia | ||
| NYG | OUT | SS Darnell Dinkins (Foot) MLB Nick Greisen (Foot) |
| DOUBTFUL | G Jason Whittle (Back) | |
| QUESTIONABLE | TE Jeremy Shockey (Toe) | |
| PROBABLE | DE Kenny Holmes (Elbow) OLB Dhani Jones (Hamstring) DT Matt Mitrione (Shoulder) CB William Peterson (Toe) DE Michael Strahan (Back) | |
| PHI | OUT | DE Derrick Burgess (Foot) |
| DOUBTFUL | FS Rashard Cook (Knee) | |
| PROBABLE | OLB Shawn Barber (Quadricep) MLB Barry Gardner (Ankle) SS Michael Lewis (Hamstring) FB Cecil Martin (Ankle) C Scott Peters (Illness) DT Corey Simon (Ankle) G John Welbourn (Leg) | |